Postdoctoral Research Fellow
Signalling mechanisms controlling synaptic plasticity in health and disease
Deadline: 22nd October 2020
Applications are invited for a postdoctoral research associate position to study the cellular and molecular mechanisms that regulate synaptic plasticity in the mammalian nervous system.
The successful applicant will study the mechanisms by which Wnt signalling regulates synaptic plasticity in the hippocampus through specific Frizzled receptors (McLeod et al, Cell Reports 2018). The postdoctoral researcher, under the direction of Professor Patricia Salinas at UCL, will take a multidisciplinary approach that uses in vivo analyses of mutant mice using state-of-the-art imaging techniques combined with the latest molecular and biochemical methods, optogenetics and electrophysiology. The researcher will also examine how Wnt-mediated synaptic plasticity influences synapse stability in the context of Alzheimer’s disease.
To view the full advert, Click Here. To submit an application, please go to UCL Jobs
If the links do not work, access the UCL Jobs page and search for the job ref 1872051 (https://www.ucl.ac.uk/work-at-ucl/search-jobs)
Deadline: 10th October 2020
Applicants are invited to apply for a research technician post to join our dynamic research team at UCL working on the mechanisms that contribute to synaptic dysfunction and degeneration in Alzheimer’s disease (AD). The applicants will use a range of transcriptomic/proteomic approaches, cell-imagining and electrophysiological techniques. The candidates will have access to state-of-the-art imaging facilities and will have the opportunity to collaborate with scientists in the ARUK Drug Discovery Institute at UCL and the Francis Crick Institute.
The post holder will have or be expecting an undergraduate or postgraduate degree in a relevant discipline (neuroscience, biology, biochemistry, etc). Working experience in molecular biology or cell imagining techniques would be advantageous.
If the links do not work, access the UCL Jobs page and search for the job ref 1871811 (https://www.ucl.ac.uk/work-at-ucl/search-jobs)
Most PhD students can join the lab by enrolling in one of UCL’s distinguished 4-year PhD programmes, such as the UCL Birkbeck MRC Doctoral Training Programme. If you are not eligible for these programmes, or would like to make an informal inquiry prior to making an application, please get in touch.