Job Opportunities

Postdoctoral researchers & Research Technicians

We are currently hiring!

Open postdoctoral position

Applications are invited to apply for a postdoctoral scientist position to work on a project aimed at elucidating the function of Wnt-Frizzled signalling in synaptic connectivity. This project will be conducted in the laboratory of Professor Patricia Salinas at UCL. The project focuses on the unravelling the mechanisms that control the levels of Wnt receptors in neurons and at synapses, a process that is crucial for the formation of neuronal connections. The project is based on our recent results published in Developmental Cell (see Teo et al., 2023, Developmental Cell 58, 2063–2079). The postdoctoral researcher will use a range of state-of-the-art cell biology and imaging techniques, gene editing in neurons to understand how Wnt receptors are modified to promote synaptic connectivity. The postdoctoral fellow will also use optogenetic approaches to study synaptic connectivity.

Applications are particularly welcome from candidates with research expertise in one of the following areas: cell imaging, post-translational modifications and cellular neurobiology and synaptic connectivity. Experience in cell imagining techniques would be very advantageous.

Informal enquiries should be addressed to Professor Patricia Salinas (email: p.salinas@ucl.ac.uk).

The closing date for applications is 28th of July 2024.

Open research technician position

Applicants are invited to apply for a research technician to work in a project aimed at elucidating the function of Wnt signalling in synaptic connectivity. This is an exciting opportunity to join Professor Patricia Salinas lab at the main campus of UCL located at the heart of London.

The project is focused on elucidating the molecular mechanisms that regulate the formation and maintenance of synapses in the rodent brain and how deficiency in Wnt signalling contributes to synapse degeneration in Alzheimer’s disease. The work is based on previous published results (see Nuria Martin-Flores et al., eLife. 2024 Jan 29;12:RP89453. doi: 10.7554/eLife.89453).

The applicant will use a range of state-of-the-art imaging techniques, transcriptomic and proteomic approaches as well as biochemical approaches and gene editing to understand the mechanisms that control the stability of synapses in the healthy brain and how synapses become vulnerable in neurodegenerative diseases.

Candidates should have a good first degree in a relevant life sciences discipline and have research skills applicable to this area of research.

Informal enquiries should be addressed to Professor Patricia Salinas (email: p.salinas@ucl.ac.uk).

The closing date for applications is 28th of July 2024.

PhD positions

Most PhD students can join the lab by enrolling in one of UCL’s distinguished 4-year PhD programmes, such as the UCL Birkbeck MRC Doctoral Training Programme.  If you are not eligible for these programmes, or would like to make an informal inquiry prior to making an application, please get in touch.