We are excited to share our latest paper published in Molecular Psychiatry on epigenetic repression of Wnt receptors in AD. We define a novel role for nuclear hyperactivated Sirt2 in repressing Fzd1 and Fzd7 expression via H4K16ac deacetylation in AD. We propose Sirt2 as an attractive target to ameliorate AD pathology.
Author: Salinas_Lab_UCL
Check out our latest paper on the interplay between Wnt, NOS and LTP
We are excited to share our newest publication on the effects of nitric oxide signalling on the formation of multi-innervated spines. We found that Wnt7a stimulates the formation of MISs via the activation of postsynaptic Dvl1 and retrograde nNOS signalling. The results are published in Frontiers in Synaptic Neuroscience (link).
You can find this and the rest of our publications on our Publications page.
Check out our latest paper describing a role for Wnts in synaptic plasticity
Patricia Molina Molina awarded best overall student for Neuroscience MSc Degree 2017
We congratulate our past student Patricia Molina Molina on her Neuroscience MSc distinction and for winning the best overall student. Good luck in your PhD at the Institute of Neurosciences, Universitat Autònoma de Barcelona.
Postdoctoral Fellow Awarded the UCL Neuroscience Early Career prize
Dr Aude Marzo, a postdoctoral fellow in the lab, was awarded the UCL Neuroscience Early Career prize (June 2017) in the Advanced Category. This award was based on her work recently published in Current Biology. (http://www.ucl.ac.uk/research/domains/neuroscience/events/2017NeuroscienceSymposium)
Postdoctoral Fellow Awarded EU H2020 Marie Curie Fellowship
Dr Ernest Palomer-Villa, a postdoctoral fellow in the lab, was awarded EU H2020 Marie Curie Fellowship to work on the mechanisms that lead to the deregulation of Wnt components in Alzheimer’s disease.
