Check out our latest preprint on epigenetic repression of Wnt receptors in AD

We are excited to share our latest preprint on epigenetic repression of Wnt receptors in AD. We define a novel role for nuclear hyperactivated Sirt2 in repressing Fzd1 and Fzd7 expression via H4K16ac deacetylation in AD. We propose Sirt2 as an attractive target to ameliorate AD pathology.

https://www.biorxiv.org/content/10.1101/2021.05.19.444683v3

Leave a Reply